Multiple ScleroSiS – indian perSpective

Multiple sclerosis (MS) is an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system (CNS), destroying the myelin and the axon in variable degrees. The disease is characterized initially by episodes of reversible neurologic deficits. In most patients, these episodes are followed by progressive neurologic deterioration over time. The cause of the disease is not known, but it likely involves a combination of genetic susceptibility and a nongenetic trigger, such as a virus, low vitamin D levels, or environmental factors, that together result in a self-sustaining MS is an inflammatory, demyelinating disease of the CNS.1,2